Saina Hot Sale CAS 7361-61-7 Xylazine cannabinoids paʻepaʻe paʻepaʻe
Fa'asologa o vaila'au
upu tutusa:
2-(2,6-dimethylanilino)-5,6-dihydro-4h-1,3-thiazine;
2-(2,6-dimethylphenylamino) -4h-5,6-dihydro-1,3-thiazine;
5,6-dihydro-2-(2,6-xylidino)-4h-1,3-thiazine;
5,6-dihydro-2-(2,6-xylidino) -4h-3-thiazine;
2-(2,6-Dimethylphenylamino) -5,6-dihydro-4H-thiazine;
Xylazine Base & HCL;
Xylazine,2-(2,6-Dimethylphenylamino) -5,6-dihydro-4H-thiazine hydrochloride;
Xylazine (200 mg)
Fa'amatalaga
Xylazine o se agonist o α2-adrenergic receptors (Ki = 194 nM).O se analog o le clonidine, o le α2-adrenergic receptor agonist faʻaaogaina e faʻaitiitia ai le toto.O le Xylazine e faʻaaogaina mo le faʻamaʻi, faʻamaʻi, ma faʻamaʻi i meaola e le o ni tagata.O lo'o maua fo'i lenei oloa e avea o se fa'ata'ita'iga fa'ata'ita'iga.
OriginatorXylazine, Bayer
Fa'aoga
Antinociceptive;Alpha-2 adrenergic agonist
Fa'aoga
Xylazine o se vasega α2 o le adrenergic receptor agonist.Xylazine o se analoque clonidine e galue i luga o presynaptic ma postsynaptic receptors o se 2-adrenergic agonist.
Fa'agasologa o Gaosi
2,6-Dimethylphenyl isothiocyanate, 31.0 g (0.2 mole), saunia mai le 2,6-dimethylaniline ma thiophosgene, na faʻapipiʻiina i lalo ifo i le 15 min i se faʻalavelave faʻafefeteina o le 15.0 g (0.2 mole) o le 3-aminopropanol-1 i totonu. 100 ml o le eter.Na amata ona pupuna le eter.O le faʻafefeteina i lalo o le reflux na faʻaauau pea mo le 30 minute, ona faʻaumatia lea o le eter.O le toega na togafitia i le 100 ml o le hydrochloric acid concentrated ma kuka i lalo o le reflux mo le 30 min.Ina ua maeʻa le malulu, sa faʻafefeteina i le vai, faʻamama saoloto mai mea leaga, ma faʻapipiʻi le faʻavae e ala i le faʻaopoopoina o le faʻaogaina o le sodium hydroxide solution.Pe a toe faʻamaʻi mai le benzene-ligroin, o le mea e maua ai le 2- (2,6- dimethyl-phenylamino) -4H-5,6-dihydro-1,3-thiazine, faʻafefeteina 140-142 ° C (e maua ai le 90% o le faʻataʻitaʻiga. ).
Galuega Fa'afoma'i
Fa'agata, fa'ama'i
Fa'amatalaga Lautele
Xylazine e solu i le methanol (50 mg/ml), e maua ai se vaifofo manino, leai se lanu.E solu fo'i i le HCl acid fa'afefiloi ma le chloroform.O le Xylazine e toetoe lava a le mafai ona faʻafefe i le vai ma i vaifofo alkali.
Biochem/physiol Gaioiga
Xylazine pe a faʻaaogaina faʻatasi ma le ketamine e manatu o se vailaʻau malosi ma saogalemu i manu faʻataʻitaʻi.Ua iloa e siitia ai le fa'asa'olotoina o le kulukose i le ate, lea e fa'ateleina ai le hyperglycemia.
Faiga o gaioiga
Xylazine o loʻo faʻatauina e avea ma masima hydrochloride e pei o Rompun (100 mg / mL) ma Anased (20 mg / mL) vaifofo tui mo le faʻaogaina o solofanua ma maile.O gaioiga a le xylazine e mafai ona fesuiaʻi e ala i le faʻaaogaina o le yohimbine, o se indolalkylamine alkaloid, e poloka ai na α2-adrenoreceptors e faʻaosofia e le xylazine.
Fa'amatalaga Saogalemu
Oona e ala i le inuina, subcutaneous, ma auala tui.A'afiaga fa'aletagata: suiga ile gaioiga ole afi, pa'u ile toto toto, miosis, mafiafia pleural, fa'aitiitia le fua o le fatu, moe.A fa'avevela se'ia pala, e fa'aulu mai ai le asu o'ona o le NOx ma le SOx
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